Our Work
CBRNE Defense

CBRNE Defense From its inception, Gryphon Scientific has addressed some of the most complex problems in homeland security. Gryphon advises state and federal governments on CBRNE hazards and countermeasures to defend the homeland against acts of terrorism.

» Projects: CBRN Integrated Technical/Logistics and Proficiency Management Support
Chemical Incident Modeling and Gap Assessment
Establishing Requirements for Urban Biodefense Systems
End to End Analysis of Attacks with Antibiotic Resistant Biological Agents
Providing Technical Expertise on CBR Hazards
Evaluating Field-Deployable Biochemical Assays
Efficacy of Medical Countermeasures Against CBR Agents
Nuclear Attack Models
CBRN Integrated Technical/Logistics and Proficiency Management Support

For the Pentagon Force Protection Agency (PFPA) Chemical Biological Radiological Nuclear Explosives Response Division (CRD), the Gryphon team provides technical support to include program management, prime vendor procurement, inventory management, maintenance, and proficiency management. Our team has experience managing the technical and logistical aspects of a CBRNE response program and uses a sustained approach that ensures continuity of CRD operations with minimum disruption. We are also well-versed in developing and executing routine training products, instructing on various topics associated with CBRNE and all hazards and emergency response, practical exercises, CBRN responder proficiency assessments, and training coordination and records management.

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Chemical Incident Modeling and Gap Assessment

In a project for the Agency for Healthcare Research and Quality (AHRQ) of HHS, Gryphon was part of a team that built a software-based tool that enables local emergency planners to estimate the medical resources needed to respond to incidents involving chemical, biological and radiological incidents. The tool calculates the medical needs required by any urban area in the US to respond to attacks with chemical weapons, toxic industrial chemicals (TICs), contagious and non-contagious biological agents, natural disease outbreaks, radiological dispersion devices, improvised nuclear devices, high-energy radioactive point sources and high explosives (covering the entire CBRNE spectrum) by leveraging existing models of source terms, exposure and effects. Furthermore, the Gryphon team developed the module that produces casualty estimates (including the time-dependent appearance of casualties) that would result from these incidents through the use of sophisticated source terms and dispersion, epidemiology and pathogenicity/toxicity models.

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Establishing Requirements for Urban Biodefense Systems

For a project with the Department of Homeland Security’s Science and Technology Directorate, Gryphon Scientific helped set the requirements for a generation of urban biodefense systems. Gryphon also lead an evaluation of the first generation BioWatch system for the Office of Comparative Studies of the Science and Technology Directorate, determining what an adversary could discern about the logistics, assays, deployment and ConOps of the BioWatch system. Gryphon then analyzed how that information could be used to render a biological attack undetectable to the system. The study culminated in recommendations to address these vulnerabilities, several of which were adopted in the 2nd and 3rd generation (Gen3) BioWatch Systems.

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End to End Analysis of Attacks with Antibiotic Resistant Biological Agents

Gryphon Scientific was chosen by name to perform an end-to-end analysis of attacks with antibiotic resistant biological agents for the Department of Homeland Security’s Science and Technology Directorate. We studied the feasibility of an attack with multiple-drug resistant (MDR) agents, including the viability and virulence of such agents compared to non-MDR agents, the production of such agents, the impact of the use of MDR agents and strategies to mitigate the consequences should these agents be used. The study also included an evaluation of our current ability to mitigate an attack with MDR agents, which highlighted gaps in our ability to respond. We finished the study with a section describing possible strategies to fill these gaps

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Providing Technical Expertise on CBR Hazards

For the Federal Emergency Management Agency through a contract held by the Navy Postgraduate School, Gryphon Scientific provides a subject matter expert on biological, chemical and radiological hazards for a traveling panel that lends policy and technical advice to governors, mayors and their cabinets. As part of this project, Gryphon staff have discussed issues related to large chemical releases with jurisdictions that are at the greatest risk for accidental (or intentional) TIC releases.

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Evaluating Field-Deployable Biochemical Assays

For the FBI, our staff identified and evaluated kits usable by law enforcement personnel to analyze the threat posed by suspicious white powders that may be biological agents. In this project, Gryphon not only identified and evaluated the relevant technology (and performed field trials with the technology), but also interviewed local and federal law enforcement personnel to determine how they would use such technology and determine the burden of “white powder calls” on their personnel to determine the cost/benefit of employing such technology.

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Efficacy of Medical Countermeasures Against CBR Agents

For DTRA, Gryphon is currently modeling the efficacy of medical countermeasures against chemical, biological and radiological (CBR) agents. The project began by identifying existing medical countermeasure models, evaluating each model for gaps, and prioritizing these gaps. Our team incorporated data from pathophysiology of illness caused by CBR agents to improve the fidelity of the translation of data from animal models to human disease and investigated markers of pathological findings to establish the timing of the decline countermeasure efficacy. This information in conjunction with other data extrapolated from human and animals was used to develop modeling parameters. Models were designed to allow users to input exposure data as well as prophylactic and treatment data with outputs that included casualties and loss of work. The final stage of the project will be the incorporation of the models into a model suite with a graphical user interface.

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Nuclear Attack Models

For the Department of Health and Human Services’ Assistant Secretary for Preparedness and Response, Gryphon Scientific performed a gap assessment on existing models of nuclear attacks in cities. Our analysis was quickly followed by a study, sponsored by the Department of Defense, to close the identified gaps using a Monte Carlo-based model to track the path of energetic particles emitted by the bomb in a three-dimensional computer mock-up of New York City to provide an estimate of the extent of shielding.

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